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Chaoqun   Yao MD, PhD

Associate Professor of Parasitology


Dr. Chaoqun Yao recieved MD and PhD degrees from Huazhong University of Science & Technology and the University of Georgia, respectively. He pursued postdoctoral training at Washington State University and the University of Iowa. Dr. Yao was a non-tenure track faculty member at the University of Iowa before he joined the University of Wyoming as a tenure-track assistant professor with a concomitant appointment of adjunct professor at the University of Washington. He was also the parasitology section head of Wyoming State Veterinary Laboratory. He joined Ross University School of Veterinary Medicine as an associate professor in 2014.

Dr. Yao’s research interests are molecular pathogenesis and host-parasite interaction of parasites of veterinary /medical importance. He currently studies Leishmania/leishmaniasis and Tritrichomonas foetus/trichomoniasis. He has numerous peer-reviewed publications, and is an associate editor of two journals and an editorial board member of four journals. He has organized three symposia for the annual meeting of American Society of Tropical Medicine and Hygiene.

Education

MD Huazhong University of Science & Technology Tongji Medical College

PhD Veterinary Parasitology, University of Georgia

Research

Leishmania spp. And leishmaniasis

Parasitic diseases of medical/veterinary importance

Achievements

Outstanding Service as an Online Mentor, American Society for Microbiology Minority Mentoring Program 2011

MRP, Veterans’ Affairs, October 2006-September 2009

MREP, Veterans’ Affairs, April 2002-March 2005

Training Grants in Infectious Diseases & Parasitology, NIH, July 1999-March 2002

Publication Highlights

Yao C, Köster LS. 2015 Tritrichomonas foetus infection, a cause of chronic diarrhea in the domestic cat. BMC Veterinary Research 46: 35 DOI: 10.1186/s13567-015-0169-0 http://www.veterinaryresearch.org/content/46/1/35

Jin Y+, Schumaker B, Logan J and Yao C. 2014. Risk factors associated with bovine trichomoniasis in beef cattle determined by a questionnaire. Journal of Medical Microbiology 63: 896-902. http://jmm.sgmjournals.org/content/journal/jmm/10.1099/jmm.0.074971-0#tab2

Yao C, Gaur Dixit U, Barker J, Teesch LM, Love-Homan L, Donelson JE, Wilson ME. Attenuation of Leishmania metacyclic promastigotes by sterol depletion. Infection and Immunity. 2013;81:2507-2517. http://iai.asm.org/content/81/7/2507.full

Yao C. Diagnosis of Tritrichomonas foetus-infected bulls, an ultimate approach to eradicate bovine trichomoniasis in US cattle? Journal of Medical Microbiology. 2013;62:1-9. http://jmm.sgmjournals.org/content/journal/jmm/10.1099/jmm.0.047365-0#tab2

Yao C. Major surface protease (MSP, or GP63) of trypanosomatids, one size fits all? Infection and Immunity. 2010;78:22-31. http://iai.asm.org/content/78/1/22.full

Yao C, Li Y, Donelson JE, Wilson ME. Proteomic examination of Leishmania chagasi plasma membrane proteins: contrast between avirulent and virulent (metacyclic) parasite forms. Proteomics – Clinical Applications. 2010;4:4-16. http://onlinelibrary.wiley.com/enhanced/doi/10.1002/prca.200900050/

Hsiao CC, Yao C, Storlie P, Donelson JE, Wilson ME. The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi. Molecular and Biochemical Parasitology. 2008;157:148-159. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713036/

Yao C, Donelson JE, Wilson ME. Internal and surface-localized MSP of Leishmania spp. and their differential release from promastigotes. Eukaryotic Cell. 2007;6:1905-1912. http://ec.asm.org/content/6/10/1905.long

Yao C, Luo J, Hsiao C, Donelson JE, Wilson ME. Leishmania chagasi: A tetracycline-inducible cell line driven by T7 RNA polymerase. Experimental Parasitology. 2007;116:205-213. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231517/

Yao C, Luo J, Storlie P, Donelson JE, Wilson ME. Multiple products of the Leishmania chagasi major surface protease (MSP or GP63) gene family. Molecular and Biochemical Parasitology. 2004;135:171-183.

Yao C, Donelson JE, Wilson ME. The major surface protease (MSP, or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function. Molecular and Biochemical Parasitology. 2003;132:1-16.

Shompole S, Yao C, Cheng X, Knox D, Johnson S, Jasmer DP. Distinct characteristics of two intestinal protein components discriminated by using fenbendazole and a benzimidazole resistant isolate of Haemonchus contortus. Experimental Parasitology. 2002;101:200-209.

Yao C, Leidal KG, Brittingham A, Tarr DE, Donelson JE, Wilson ME. Biosynthesis of the major surface protease GP63 of Leishmania chagasi. Molecular and Biochemical Parasitology. 2002;121:119-128.

Yao C, Jasmer DP. Trichinella spiralis-infected muscle cells: Abundant RNA polymerase II in nuclear speckle domains colocalizes with nuclear antigens. Infection and Immunity. 2001;69:4065-4071. http://iai.asm.org/content/69/6/4065.full

Jasmer DP, Yao C, Rehman A, Johnson S. Multiple lethal effects induced by a benzimidazole anthelmintic in the anterior intestine of the nematode Haemonchus contortus. Molecular and Biochemical Parasitology. 2000;105:81-90.

Yao C, Jasmer DP. Nuclear antigens in Trichinella spiralis infected muscle cells: nuclear extraction, compartmentalization and complex formation. Molecular and Biochemical Parasitology. 1998;92:207-218.

Yao C, McGraw RA, Prestwood AK. A complementary DNA encoding an antigen from Trichinella spiralis muscle larvae and its analog from Trichinella T5 of bobcat origin: Sequence, cloning and expression. International Journal for Parasitology. 1997;27:425-430.

Yao C, Prestwood AK, McGraw RA. Trichinella spiralis (T1) and Trichinella T5: A comparison using animal infectivity and molecular biological techniques. Journal of Parasitology. 1997;83:88-95.

Current Projects

Parasitic diseases of the skeletal muscles, myocardium and lungs of the small Indian Mongoose (Herpestes javanicus).

Tritrichomonas foetus infection in the domestic cats in St. Kitts.

Giardia duedenalis & Trichuris trichura in the vervet monkey.

Trichinella spp. infections in the domestic pigs on St. Kitts & Nevis.