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Jose   Godoy DVM, PhD

Assistant Professor of Veterinary Physiology

José Godoy Berthet studied Veterinary Medicine at the Catholic University of Temuco, Chile. After a short experience as clinical veterinarian he went to Germany in 2002 where he started his scientific career. 2003-2007 he conducted his research at the Institute for Veterinary Pharmacology and Toxicology, Justus Liebig University of Giessen, Germany, obtaining his PhD (Dr. med. vet.) in 2007. Dr. Godoy worked as Postdoc at the Institute for Cytobiology of the Philipps University in Marburg, Germany (2007-2011) and as university assistant at the Institute for Veterinary Physiology, University of Veterinary Medicine in Vienna, Austria (2011-2015), where he discovered his passion for teaching.

 

Education

Veterinary Medicine, Catholic University of Temuco, Chile (BSc)
Doctor of Veterinary Medicine, Justus Liebig University Giessen, Germany (PhD)


Research

Redox-regulatory proteins in ischemic pathologies
Oxidative stress in veterinary medicine

 

Achievements

Nominated as Teacher of the Year, University of Veterinary Medicine Vienna, Austria (2014 and 2015)

 

Publication Highlights

Hanschmann EM, Godoy JR, Berndt C, Hudemann C, Lillig CH. Thioredoxins, glutaredoxins, and peroxiredoxins - molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling. Antioxid Redox Signal 2013 Nov 1;19(13):1539-605

LINK: http://online.liebertpub.com/doi/abs/10.1089/ars.2012.4599

Bräutigam L, Schütte LD, Godoy JR, Prozorovski T, Gellert M, Hauptmann G, Holmgren A, Lillig CH, Berndt C. Vertebrate-specific glutaredoxin is essential for brain development. Proc Natl Acad Sci U S A 2011 Dec 20;108(51):20532-7

LINK: http://www.pnas.org/content/108/51/20532.long

Godoy JR, Oesteritz S, Hanschmann EM, Ockenga W, Ackermann W, Lillig CH. Segment-specific overexpression of redoxins after renal ischemia and reperfusion: protective roles of glutaredoxin 2, peroxiredoxin 3, and peroxiredoxin 6. Free Radic Biol Med 2011 Jul 15;51(2):552-61

Hoffmann B, Uzarska MA, Berndt C, Godoy JR, Haunhorst P, Lill R, Lillig CH, Mühlenhoff U. The multi-domain thioredoxin-monothiol glutaredoxins represent a distinct functional group. Antioxid Redox Signal 2011 Jul 1;15(1):19-30

Godoy JR, Funke M, Ackermann W, Haunhorst P, Oesteritz S, Capani F, Elsässer HP, Lillig CH.  Redox atlas of the mouse: Immunohistochemical detection of glutaredoxin-, peroxiredoxin-, and thioredoxin-family proteins in various tissues of the laboratory mouse. Biochim Biophys Acta 2011 1810(1):2-92

Hanschmann EM, Lönn ME, Schütte LD, Funke M, Godoy JR, Eitner S, Hudemann C, Lillig CH. Both thioredoxin 2 and glutaredoxin 2 contribute to the reduction of the mitochondrial 2-Cys peroxiredoxin Prx3. J Biol Chem 2010 285(52):40699-705

LINK: http://www.jbc.org/content/285/52/40699.long

Mühlenhoff U, Molik S, Godoy JR, Uzarska MA, Richter N, Seubert A, Zhang Y, Stubbe J, Pierrel F, Herrero E, Lillig CH, Lill R. Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metabolism 2010 12(4):373-85

LINK: http://www.sciencedirect.com/science/article/pii/S1550413110002664

Haunhorst P, Berndt C, Eitner S, Godoy JR, Lillig CH. Characterization of the human monothiol glutaredoxin 3 (PICOT) as iron-sulfur protein. Biochem Biophys Res Commun 2010 394(2):372-6

Hudemann C, Lönn ME, Godoy JR, Avval FZ, Capani F, Holmgren A, Lillig CH.  Identification, expression patterns and characterization of mouse glutaredoxin 2 isoforms. Antioxid Redox Signal 2009 11(1):1-14

Geyer J, Fernandes CF, Döring B, Burger S, Godoy JR, Rafalzik S, Hübschle T, Gerstberger R, Petzinger E. Cloning and molecular characterization of the orphan carrier protein Slc10a4: Expression in cholinergic neurons of the rat central nervous system. Neuroscience 2008 152(4):990-1005
 

Interests

Cell Biology; Impact of Genetic Defects/Polymorphisms in Pharmacologic Therapy; Molecular Biology Methods; Therapeutic Application of Redox Proteins.