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Michel   Vandenplas PhD

Senior Scientist


BSC Biochemistry/Microbiology, University of Stellenbosch, South Africa
BSC, HONS Medical Biochemistry, University of Stellenbosch, South Africa
MS Medical Biochemistry, University of Stellenbosch, South Africa
PHD Medical Biochemistry, University of Stellenbosch, South Africa

Publication Highlights

Kwon S, Moore JN, Robertson TP, Hurley DJ, Wagner B, Vandenplas ML. Disparate effects of LPS infusion and carbohydrate overload on inflammatory gene expression in equine laminae. Vet Immunol Immunopathol. 2013;155(1-2):1-8.

Gores-Lindholm AR, LeBlanc MM, Causey R, Hitchborn A, Fayrer-Hosken RA, Kruger M, Vandenplas ML, Flores P, Ahlschwede S. Relationships between intrauterine infusion of N-acetylcysteine, equine endometrial pathology, neutrophil function, post-breeding therapy, and reproductive performance. Theriogenology. 2013;80(3):218-27.

Lawrence J, Karpuzoglu E, Vance A, Vandenplas M, Saba C, Turek M, Gogal RM Jr. Changes in γ-H2AX expression in irradiated feline sarcoma cells: an indicator of double strand DNA breaks. Res Vet Sci. 2013;94(3):545-8.

Schmiedt CW, Nelson SA, Brainard BM, Brown CA, Vandenplas M, Hurley DJ. Bilateral renal ischemia as a model of acute kidney injury in cats. Res Vet Sci. 2012;93(2):950-9.

Regan DP, Aarnio MC, Davis WS, Carmichael KP, Vandenplas ML, Lauderdale JD, Moore PA. Characterization of cytokines associated with Th17 cells in the eyes of horses with recurrent uveitis. Vet Ophthalmol. 2012;15(3):145-52.

Kwon S, Gewirtz AT, Hurley DJ, Robertson TP, Moore JN, Vandenplas ML. Disparities in TLR5 expression and responsiveness to flagellin in equine neutrophils and mononuclear phagocytes. J. Immunol. 2011;186(11):6263-70.


Research Interests: Studies on the role and regulation of the innate immune system in equine colic and lameness at the cellular and molecular level.

Providing molecular and cellular biology technical support to clinical researchers in diverse areas of veterinary medicine.

Teaching Interests: Innate immunity, molecular biology, control of gene expression, intracellular signal, transduction, laboratory techniques.