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Aspinas   Chapwanya BVSc, BSc, MVM, PhD

Assistant Professor, Theriogenology


Education

BSC Faculty of Agriculture, University of Zimbabwe

BVSC Faculty of Veterinary Science, University of Zimbabwe

MVM Faculty of Veterinary Medicine, University College Dublin

PHD School of Biochemistry and Immunology, Trinity College Dublin

Publication Highlights

Foley C, Chapwanya A, Callanan JJ, Whiston R, Miranda-CasoLuengo R, Lu J, Meijer WG, Lynn DJ, O’Farrelly C, Meade KG. 2015. Dysregulation of Endometrial Inflammation Precedes the Development of Cytological Endometritis. BMC Genomics.

Kanengoni AT, Chimonyo M, Tasara T, Cormican P, Chapwanya A, Ndimba B, Dzama K. 2015. Genomic analysis of faecal microbial populations of South African Windsnyer-type indigenous pigs (SAWIP) and Large White x Landrace (LWxLR) crosses fed diets containing ensiled maize cobs. FEMS Microbiology Letter.

Chapwanya A,
Usman AY, Irons PC. 2015. Comparative aspects of immunity and vaccination in human and bovine trichomoniasis: a review. Tropical Animal Health and Production.

Esposito G, Irons PC, Webb EC, Chapwanya A. Interactions between negative energy balance, metabolic diseases, uterine health and immune response in transition dairy cows: A Review. Journal of Animal Reproduction. 2013.

Foley C, Chapwanya A, Creevey C, Narciandi F, Morris D, Kenny E, Cormican P, Callanan JJ, O’Farrelly C, Meade KG. Global endometrial transcriptomic profiling during involution: transient immune activation precedes tissue proliferation and repair in postpartum healthy beef cows. BMC Genomics. 2013;13:489 doi:10.1186/1471-2164-13-489.

Whelehan CJ, Meade KG, Chapwanya A, Narciandi F, Lloyd AT, O’Farrelly C. Characterisation of the Cathelicidin gene repertoire and expression profile in cattle. BMC Genomics. 2013

Chapwanya A, Meade KG, Doherty ML, Callanan JJ, O’Farrelly C. Escherichia coli induce acute phase proteins (APPs) production by bovine endometrial epithelial cells in vitro. Journal of Veterinary Immunology and Immunopathology. 2012;doi.org/10.1016/j.vetimm..09.042.

Chapwanya A, Meade KG, Foley C, Narciandi F, Evans ACO, Doherty ML, Callanan JJ, O’Farrelly C. The postpartum endometrial inflammatory response: a normal physiological event with potential implications for bovine fertility. Journal of Reproduction, Fertility and Development. 2012;(8):1028-39 doi:10.1071/RD11153.

Narciandi F, Lloyd AT, Chapwanya A, O'Farrelly C, Meade KG. Reproductive tissue-specific expression profiling and genetic variation across a 19 gene bovine β-defensin cluster. Immunogenetics. 2011;DOI10.1007/s00251-011-0551-7.

Chapwanya A, Meade KG, Stanley P, Narciandi F, Mee JF, Doherty ML, Callanan JJ, O’Farrelly C. Endometrial biopsy – a useful clinical and research tool in bovine reproduction. Theriogenology. 2010;73:988-994.

Chapwanya A, Meade KG, Doherty ML, Callanan JJ, Mee JF, O’Farrelly C. Histopathological and molecular evaluation of Holstein-Friesian cows postpartum: toward an improved understanding of uterine innate immunity. Theriogenology. 2009;71(9):1396–1407.

Chapwanya A, Clegg T, Stanley P, Vaughan L. Comparison of the Immulite and RIA assay methods for measuring peripheral blood progesterone levels in Greyhound bitches. Theriogenology. 2008;70(5):795-799.

Cormican P, Meade KG, Cahalane S, Narciandi F, Chapwanya A, Lloyd AT, O’Farrelly C. Evolution, expression and effectiveness in a cluster of novel bovine beta-defensins. Journal of Immunogenetics. 2008;60(3-4):147-156.

Presentations

Foley C, Chapwanya A, Callanan JJ, O’ Farrelly C, Meijer W, Meade KG. Cellular, Molecular and Microbiological Profiles at Day 7 Postpartum Identifies Cows at Risk of Uterine Disease. International Conference of the European Society of Veterinary Immunology. Poland. 2013.

Foley C, Chapwanya A, Creevey C, Narciandi F, Morris D, Kenny E, Cormican P, Callanan JJ, O’Farrelly C, Meade K.G. Global endometrial transcriptomic profiling during involution: transient immune activation precedes tissue proliferation and repair in postpartum healthy beef cows. 13th International Conference of the European Society of Domestic Animal Reproduction (ESDAR). Dublin, Ireland. 2012.

Whelehan CJ, Meade KG, Chapwanya A, Lloyd AT, O’Farrelly C. Characterisation of the Cathelicidin gene repertoire and expression profile in cattle. Annual meeting of the Irish Society of Immunologists (ISI). Dublin, Ireland. 2012.

Chapwanya A, Meade KG, Foley C, Narciandi F, Evans ACO, Doherty ML, Callanan JJ, O’Farrelly C. The postpartum endometrial inflammatory response: a normal physiological event with potential implications for bovine fertility. 4th International Symposium on Animal Functional Genomics (ISAFG) Conference. Dublin, Ireland. 2011.

Narciandi F, Lloyd AT, Chapwanya A, O'Farrelly C, Meade KG. Characterisation of the reproductive tissue-specific expression profile and genetic variation across a 19 gene bovine β-defensin cluster. 4th International Symposium on Animal Functional Genomics (ISAFG) Conference. Dublin, Ireland. 2011.

Foley C, Chapwanya A, Creevey C, O’Farrelly C, Meade KG. Next-generation sequencing of the post-partum endometrial transcriptome. 4th International Symposium on Animal Functional Genomics (ISAFG) Conference. Dublin, Ireland. 2011.

Other

Research Interest: Endometrial innate immunity in postpartum cattle, Energy balance in postpartum cattle, Uterine microbial populations after calving.

Teaching Interest: Artificial Insemination, Oestrous cycle manipulation, Male and female reproductive biology.

Conference Papers

Esposito G, Chapwanya A, Webb EC, Irons PC. 2014. Possible markers of uterine and metabolic health in transition dairy cows. ADSA-ASAS-CSAS Joint Annual Meeting. South Africa

Foley C, Chapwanya A, Callanan JJ, Miranda R, Meijer WG, Lynn DJ, O’Farrelly C, Meade KG. 2014. Local and Systemic Immune Profiles at Day 7 Post-Partum Identify Dairy Cows at Risk of Uterine Disease. International Conference on Biology and Pathology of Reproduction in Domestic Animals, Olsztyn, Poland.

Nogueira de Moraes C, Maia L, e Dias Camargos M, de Paula Freitas Dell´Aqua C, da Cruz Landim F,Chapwanya A, Oba E. 2015. Analysis of viability of stromal cell from bovine endometrial tissue cryopreserved with different media. American Congress on Reproduction, Chicago, USA.

Brewer A, Chapwanya A, O’Farrelly C, Meade KG. 2015. Inflammatory gene signatures of bovine endometrial epithelial cells in association with endometritis. International Conference on Biology and Pathology of Reproduction in Domestic Animals, Gdansk, Poland.

Lim J, Callanan JJ, O’Farrelly C, Meade KG, Chapwanya A. 2015. Analysis of Systemic Changes in Cows with Subclinical Endometritis. International Conference on Biology and Pathology of Reproduction in Domestic Animals, Gdansk, Poland.