Diana Scorpio , DVM, MPH, DACLAM

Dr. Scorpio is a licensed veterinarian and has been a Diplomate of the American College of Laboratory Animal Medicine since 2004. Dr. Scorpio received her DVM from Michigan State University in 1997. She then pursued an NIH T32 Comparative Medicine fellowship at the Johns Hopkins University School of Medicine where she remained on as faculty for 8 years. During her tenure there, she also received her MPH at the Bloomberg School of Public Health. Dr. Scorpio then pursued her career internationally at the National University of Singapore and Ross University School of Veterinary Medicine before returning stateside for her present position with the Vaccine Research Center.

Education

BS, Animal Science and Veterinary Technology, University of Rhode Island
MPH, Public Health, Johns Hopkins University
DVM, Michigan State University
Post-doctoral Fellowship, Comparative Medicine, Johns Hopkins University

Certifications

Diplomate, American College of Laboratory Animal Medicine
Certification in Science of Clinical Investigation, Johns Hopkins University
Certification in Winemaking and Viticulture, University of California, Davis

Research interests

Translational Research
Saran Bao, B.S., Biologist
Rachel Vistein, DVM, PhD, Post Doc IRTA

Animal Care and Use Program
Alida Taylor, B.S., Animal Program Coordinator
Carmelo Chiedi, CMAR, RLATG, Project Manager
Marlon Dillon, B.S., CMAR, LATG, Animal Facility Specialist
Gloria Salbador, ALAT, Veterinary Technician
Lauren Gilliam, LAT, Veterinary Technician
Alicia Silvious, Veterinary Technician
 
Animal Resources
John Paul Todd, B.S., Biologist
Hana Bao, MPH, Research Support Specialist
Steven Young, LAT, NHP Project Manager
Yoav Littman, MS, LATG, NHP Behaviorist/Research Specialist
Jumagul Noor, DVM, Research Specialist
Elizabeth McCarthy, BA, LAT, Research Specialist

Achievements

2010 AALAS Pravin N. Bhatt Young Investigator Award for outstanding young scientist

Publication Highlights

Scorpio DG, Leutenegger C, Berger J, Barat NC, Madigan JE, Dumler JS. (2008) Sequential analysis of A. phagocytophilum msp2 transcription in murine and equine models of human granulocytic anaplasmosis. Clinical Vaccine Immunology, 15:418-424.

Scorpio DG, Wachtman L, Tunin R, Barat NC, Garyu J, Dumler JS. (2008) Retrospective clinical and molecular analysis of conditioned laboratory dogs (Canis familiaris) with serologic reactions to Ehrlichia canis, Borrelia burgdorferi, and Rickettsia rickettsii. Journal of the American Association of Laboratory Animal Science, 47:23-28.

Scorpio DG, Garyu J, Barat NC, Dumler JS. (2008) Anaplasma phagocytophilum propagation is enhanced in human complement-containing medium. Clinical Microbiology Infection 15(s2):48-49.

Scorpio DG, Dumler JS, Barat NC, Cook JA, Barat CE, Stillman BA, Debisceglie KC, Beall MJ, Chandrashekar R. (2011) Comparative Strain Analysis of Anaplasma phagocytophilum Infection and Clinical Outcomes in a Canine Model of Granulocytic Anaplasmosis. Vector Borne Zoonotic Disease 11(3):223-229.

Headley SA, Scorpio DG, Vidotto O, Dumler JS. (2011) Neorickettsia helminthoeca and Salmon Poisoning Disease: A review. Veterinary Journal 187(2):165-173.

André MR, Dumler JS, Scorpio DG, Teixeira RHF, Allegretti SM, Machado RZ. (2012) Molecular detection of tick-borne bacterial agents in Brazilian and exotic captive carnivores. Ticks and Tick Borne Diseases 3(4): 247-253.

Armistead JS, Morlais I, Mathias DK, Jardim JG, Joy J, Fridman A, Finnefrock AC, Bagchi A, Plebanski M, Scorpio DG, Churcher TS, Borg NA, Sattabongkot J, Dinglasan RR.  (2014) Antibodies to a single, conserved epitope in Anopheles APN1 inhibit universal transmission of Plasmodium falciparum and Plasmodium vivax malaria. Infect Immun 82(2):818-29.

Choi KS, Scorpio DG, Dumler JS. (2014) Stat1 negatively regulates immune-mediated injury with Anaplasma phagocytophilum infection. J Immunology 193(10): 5088-5098.

Vieira-Damiani G, de Paiva Diniz PPV, Pitassi LHU, Sowy S, Scorpio DG, Lania BG, Velho PENF. (2015). Bartonella clarridgeiae bacteremia detected in an asymptomatic blood donor. J Clin Microbiol 53(1): 352-356.

Pitassi LH, de Paiva Diniz PP, Scorpio DG, Drummond MR, Lania BG, Barjas-Castro ML, Gilioli R, Colombo S, Sowy S, Breitschwerdt EB, Nicholson WL, Velho PE. (2015) Bartonella spp. bacteremia in blood donors from Campinas, Brazil. PLoS Negl Trop Dis 15;9(1):e0003467.

Stewart-Jones GBE, Chuang GY, Xu K, Zhou T, Acharya P, Tsybovsky Y, Ou L, Zhang B, Fernandez-Rodriguez B, Gilardi V, Silacci-Fregni C, Beltramello M, Baxa U, Druz A, Kong WP, Thomas PV, Yang Y, Foulds KE, Todd JP, Wei H, Salazar AM, Scorpio DG, Carragher B, Potter CS, Corti D, Mascola JR, Lanzavecchia A, Kwong PD. Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4(link is external).  Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12265-12270.

Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, Chambers M, Chen X, Choi CW, Dandey VP, Doria-Rose NA, Druz A, Eng ET, Farney SK, Foulds KE, Geng H, Georgiev IS, Gorman J, Hill KR, Jafari AJ, Kwon YD, Lai YT, Lemmin T, McKee K, Ohr TY, Ou L, Peng D, Rowshan AP, Sheng Z, Todd JP, Tsybovsky Y, Viox EG, Wang Y, Wei H, Yang Y, Zhou AF, Chen R, Yang L, Scorpio DG, McDermott AB, Shapiro L, Carragher B, Potter CS, Mascola JR, Kwong PD. Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1(link is external). Nat Med. 2018 Jun;24(6):857-867.

Scorpio DG, Choi KS, Dumler JS. Anaplasma phagocytophilum-Related Defects in CD8, NKT, and NK Lymphocyte Cytotoxicity(link is external). Front Immunol. 2018 Apr 9;9:710.

Kwon YD, Chuang GY, Zhang B, Bailer RT, Doria-Rose NA, Gindin TS, Lin B, Louder MK, McKee K, O'Dell S, Pegu A, Schmidt SD, Asokan M, Chen X, Choe M, Georgiev IS, Jin V, Pancera M, Rawi R, Wang K, Chaudhuri R, Kueltzo LA, Manceva SD, Todd JP, Scorpio DG, Kim M, Reinherz EL, Wagh K, Korber BM, Connors M, Shapiro L, Mascola JR, Kwong PD. Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody(link is external). Cell Rep. 2018 Feb 13;22(7):1798-1809.

Jenkins S, Ketzis JK, Dundas J, Scorpio D. Efficacy of Minocycline in Naturally Occurring Nonacute Ehrlichia canis Infection in Dogs(link is external). J Vet Intern Med. 2018 Jan;32(1):217-221.

André MR, Dumler JS, Herrera HM, Gonçalves LR, de Sousa KC, Scorpio DG, de Santis AC, Domingos IH, de Macedo GC, Machado RZ. Assessment of a quantitative 5' nuclease real-time polymerase chain reaction using the nicotinamide adenine dinucleotide dehydrogenase gamma subunit (nuoG) for Bartonella species in domiciled and stray cats in Brazil(link is external). J Feline Med Surg. 2016 Oct;18(10):783-90.