Lorenzo Segabinazzi

Lorenzo Segabinazzi, DVM, MSc, PhD

Assistant Professor of Theriogenology
Lorenzo Segabinazzi

LSegabinazzi@rossvet.edu.kn

I am a veterinary graduate from the Federal University of Pelotas, RS, Brazil with a particular interest in Animal Reproduction. After graduating from veterinary school, I spent time in private practice as a stud farm veterinarian (equine reproduction) before returning to the University for post-graduate study. I later completed my Master’s and PhD at the São Paulo State University and University of Illinois. After completing my PhD, I took on a position as a post-doctoral fellow at Ross University School of Veterinary Medicine in 2021, and joined the faculty staff in 2022.

Education

Federal University of Pelotas, Brazil
Sao Paulo State University
Ross University

Research Interests

Animal reproduction, embryo transfer, semen biotechnology, endometritis, uterine pathologies, oviduct, biological therapies, donkey reproduction

Publication Highlights (Last 5 Years)
  1. Papa PM, Segabinazzi LGTM, Fonseca-Alves CE, Papa FO, Alvarenga MA. Intratesticular transplantation of allogenic mesenchymal stem cells mitigates testicular destruction after induced heat stress in Miniature-horse stallions. Journal of Equine Veterinary Science 2024; 132; 104961.
  2. Segabinazzi LGTM, Gilbert RO, Ambrosia R, Bergfelt D, Samper J, Peterson EW, French H. Structural and functional dynamics of the ovary and uterus during estrous cycle in donkeys in the Eastern Caribbean. Animals 2023; 13:74.
  3. French H, Segabinazzi L, Middlebrooks B, Peterson E, Schulman M, Roth R, Crampton M, Conan A, Marchi S, Gilbert T, Knobel D, Bertschinger H. Efficacy and safety of native and recombinant zona pellucida immunocontraceptive vaccines formulated with non-freund’s adjuvants in donkeys. Vaccines 2022; 10:1999.
  4. Gobato MLM, Segabinazzi LGTM, Scheeren VFC, Bandeira RS, Freitas-Dell´Aqua CP, Dell´Aqua Jr JA, Papa FO. Ability of donkey sperm to tolerate cooling: effect of extender base and removal of seminal plasma on sperm parameters and fertility rates in mares. Frontier in Veterinary Science 2022; 9:1011899.
  5. Segabinazzi LGTM, Roberts BN, Peterson EW, Ambrosia R, Bergfelt D, Samper J, French H, Gilbert RO. Early pregnancy in jennies in the Caribbean: corpus luteum development and progesterone production, uterine and embryo dynamics, conceptus growth and maturation. Animals 2022; 12:127.
  6. Segabinazzi LGTM, Landers M, Kent A, Peterson E, Gilbert R, French H. Efficacy and side effects of low single doses of cloprostenol sodium or dinoprost tromethamine to induce luteolysis in donkeys. J Equine Vet Sci 2021; 107: 103774.
  7. Segabinazzi LGTM, Scheeren VFC, Freitas-Dell'Aqua CP, Papa FO, Alvarenga MA, Dell'Aqua Jr JA, Canisso IF. Cholesterol-loaded cyclodextrin addition to skim milk-based extender enhances donkey semen cooling and fertility in horse mares. J Equine Vet Sci 2021; 105: 103719.
  8. Segabinazzi LGTM, Andrade Jr. LRP, Alvarenga MA, Dell’Aqua Jr. JA, Canisso IF. Use of intravaginal progesterone-releasing device results in similar pregnancy rates and losses to long-acting progesterone to synchronize acyclic embryo recipient mares. Vet Sci 2021; 8:190.
  9. Rodrigues LT, Segabinazzi LGTM, Oliveira SN, Frasson M, Papa FO. Two successful embryo transfers of mini-donkey embryos in Brazilian Northeastern jennies using an alternative method: Case report. Reprod Domest Anim 2021; 56: 1470-1474.
  10. Segabinazzi LGTM, Podico G, Rosser MF, Nanjappa SG, Alvarenga MA, Canisso IF. Three manual noncommercial methods to prepare equine platelet-rich plasma. Animals 2021; 11:1478.
  11. Segabinazzi LGTM, Canisso IF, Podico G, Cunha LL, Novello G, Rosser MF, Loux SC, Lima FS, Alvarenga MA. Intrauterine blood plasma platelet-therapy mitigates persistent breeding-induced endometritis, reduces uterine infections, and improves embryo recovery in mares. Antibiotics 2021; 10: 490.
  12. Segabinazzi LGTM, Tongu EAO, Alvarenga ML, Monteiro A, Papa FO, Alvarenga MA. Allogenic mesenchymal stem cell-conditioned medium does not affect sperm parameters and mitigates early endometrial inflammatory responses in mares. Theriogenology 2021; 169: 1-8.
  13. Cavalero TMS, Segabinazzi LGTM, Scheeren VFC, Freitas-Dell’Aqua CP, Papa FO. Characterization of semen collected by pharmacologically induced ejaculation from a stallion with seminal vesiculitis. Reprod Domest Anim 2020;00: 1-4.
  14. Andrade Junior LRP, Segabinazzi LGTM, Oliveir SN, Dell’Aqua JA, Papa FO. An approch to rescue the fertility of stallions with high level of hemospermia. Reprod Domest Anim 2020;00, 1-5.
  15. Oliveira SN, Andrade Junior LRP, Silva LFMC, Araujo EAB, Hayashi RM, Segabinazzi LGTM, Alvarenga MA, Dell’Aqua CPF, Dell’Aqua Jr. JA, Papa FO. Fractionated semen collection as a tool to rescue fertility in stallions with seminal vesiculitis. Theriogenology 2020;157, 110-120.
  16. Canisso IF, Segabinazzi LGTM, Fedorka CE. Persistent breeding-induced endometritis in mares - A multifaceted challenge: from clinical aspects to immunopathogenesis and pathobiology. Int J Mol Sci 2020; 21(4).
  17. Friso AM, Segabinazzi LGTM, Cyrino M, Correal SB, Freitas-Dell’Aqua CP, Carmo M, Dell'aqua JA, Miró J, Papa FO Alvarenga MA. Periovulatory administration of firocoxib did not alter ovulation rates and mitigated post-breeding inflammatory response in mares. Theriogenology 2019; 138, 24-30.
  18. Alvarenga MA, Segabinazzi LG. Application of Misoprostol as a treatment of unexplained infertility in mares. J Equine Vet Sci 2018; 71,46-50.
  19. Segabinazzi LG, Friso AC, Sebastian B, Crespilho AM, Dell'aqua JA, Miró J, Papa FO, Alvarenga MA. Uterine clinical findings, fertility rate, leucocyte migration, and COX-2 protein levels in the endometrial tissue of susceptible mares treated with platelet-rich plasma before and after AI. Theriogenology 2017; 104:120-12.
Professor showing veterinarian students how to use microscopes
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